BGN-UTRN Fusion FISH Probe
The BGN-UTRN Fusion FISH Probe is used to confirm a fusion of the BGN and UTRN genes. The fusion of the BGN and UTRN genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BGN-UTRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-RERE | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-REOR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-REGO | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-REGR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-REAQ | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-ORRE | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-OROR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-ORGO | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-ORAQ | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GORE | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GOOR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GOGO | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GOGR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GOAQ | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GRRE | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GROR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GRGO | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GRGR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-GRAQ | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-AQRE | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-AQOR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-AQGO | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-AQGR | 20 (40 μL) | 200 μL |
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| BGN-UTRN-20-AQAQ | 20 (40 μL) | 200 μL |
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BGN Gene Summary
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015]
Gene Name: Biglycan
Chromosome: CHRX: 152760346 -152775004
Locus: Xq28
UTRN Gene Summary
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Utrophin
Chromosome: CHR6: 144612872 -145174170
Locus: 6q24.2
Gene Diseases
The BGN UTRN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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