BCL7A-KCNIP3 Fusion FISH Probe
The BCL7A-KCNIP3 Fusion FISH Probe is used to confirm a fusion of the BCL7A and KCNIP3 genes. The fusion of the BCL7A and KCNIP3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCL7A-KCNIP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| BCL7A-KCNIP3-20-AQAQ | 20 (40 μL) | 200 μL |
|
BCL7A Gene Summary
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: BCL Tumor Suppressor 7A
Chromosome: CHR12: 122459860 -122499950
Locus: 12q24.31
KCNIP3 Gene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Interacting Protein 3
Chromosome: CHR2: 95963071 -96051825
Locus: 2q11.1
Gene Diseases
The BCL7A KCNIP3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|