BCL2L14-ETV6 Fusion FISH Probe
The BCL2L14-ETV6 Fusion FISH Probe is used to confirm a fusion of the BCL2L14 and ETV6 genes. The fusion of the BCL2L14 and ETV6 genes has been associated with Breast Invasive Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCL2L14-ETV6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-RERE | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-REOR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-REGO | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-REGR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-REAQ | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-ORRE | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-OROR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-ORGO | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GORE | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GOOR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GOGO | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GOGR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GRRE | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GROR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GRGO | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GRGR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-AQRE | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-AQOR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-AQGO | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-AQGR | 20 (40 μL) | 200 μL |
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| BCL2L14-ETV6-20-AQAQ | 20 (40 μL) | 200 μL |
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ETV6 Gene Summary
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
Gene Name: ETS Variant 6
Chromosome: CHR12: 11802787 -12048325
Locus: 12p13.2
BCL2L14 Gene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]
Gene Name: BCL2 Like 14
Chromosome: CHR12: 12223877 -12252627
Locus: 12p13.2
Gene Diseases
The BCL2L14 ETV6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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