BCL2L12-FLT3LG Fusion FISH Probe
The BCL2L12-FLT3LG Fusion FISH Probe is used to confirm a fusion of the BCL2L12 and FLT3LG genes. The fusion of the BCL2L12 and FLT3LG genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCL2L12-FLT3LG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-RERE | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-REOR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-REGO | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-REGR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-REAQ | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-ORRE | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-OROR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-ORGO | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GORE | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GOOR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GOGO | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GOGR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GRRE | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GROR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GRGO | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GRGR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-AQRE | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-AQOR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-AQGO | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-AQGR | 20 (40 μL) | 200 μL |
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| BCL2L12-FLT3LG-20-AQAQ | 20 (40 μL) | 200 μL |
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FLT3LG Gene Summary
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Gene Name: Fms Related Tyrosine Kinase 3 Ligand
Chromosome: CHR19: 49977465 -49989488
Locus: 19q13.33
BCL2L12 Gene Summary
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: BCL2 Like 12
Chromosome: CHR19: 50168398 -50177173
Locus: 19q13.33
Gene Diseases
The BCL2L12 FLT3LG Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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