BCL2L11-AFMID Fusion FISH Probe
The BCL2L11-AFMID Fusion FISH Probe is used to confirm a fusion of the BCL2L11 and AFMID genes. The fusion of the BCL2L11 and AFMID genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCL2L11-AFMID-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-RERE | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-REOR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-REGO | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-REGR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-REAQ | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-ORRE | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-OROR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-ORGO | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GORE | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GOOR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GOGO | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GOGR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GRRE | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GROR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GRGO | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GRGR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-AQRE | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-AQOR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-AQGO | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-AQGR | 20 (40 μL) | 200 μL |
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| BCL2L11-AFMID-20-AQAQ | 20 (40 μL) | 200 μL |
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BCL2L11 Gene Summary
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]
Gene Name: BCL2 Like 11
Chromosome: CHR2: 111878490 -111926022
Locus: 2q13
AFMID Gene Summary
The Arylformamidase (AFMID) gene is located on chr17 :76183397-76203782 at 17q25.3.
Gene Name: Arylformamidase
Chromosome: CHR17: 76183397 -76203782
Locus: 17q25.3
Gene Diseases
The BCL2L11 AFMID Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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