BCL11B-MIPOL1 Fusion FISH Probe
The BCL11B-MIPOL1 Fusion FISH Probe is used to confirm a fusion of the BCL11B and MIPOL1 genes. The fusion of the BCL11B and MIPOL1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCL11B-MIPOL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-RERE | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-REOR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-REGO | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-REGR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-REAQ | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-ORRE | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-OROR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-ORGO | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GORE | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GOOR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GOGO | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GOGR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GRRE | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GROR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GRGO | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GRGR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-AQRE | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-AQOR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-AQGO | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-AQGR | 20 (40 μL) | 200 μL |
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| BCL11B-MIPOL1-20-AQAQ | 20 (40 μL) | 200 μL |
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BCL11B Gene Summary
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Gene Name: B-cell CLL/lymphoma 11B
Chromosome: CHR14: 99635624 -99737822
Locus: 14q32.2
MIPOL1 Gene Summary
This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]
Gene Name: Mirror-image Polydactyly 1
Chromosome: CHR14: 37667117 -38020464
Locus: 14q13.3-q21.1
Gene Diseases
The BCL11B MIPOL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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