BCAT1-PRB3 Fusion FISH Probe
The BCAT1-PRB3 Fusion FISH Probe is used to confirm a fusion of the BCAT1 and PRB3 genes. The fusion of the BCAT1 and PRB3 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCAT1-PRB3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-RERE | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-REOR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-REGO | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-REGR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-REAQ | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-ORRE | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-OROR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-ORGO | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GORE | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GOOR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GOGO | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GOGR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GRRE | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GROR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GRGO | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GRGR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-AQRE | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-AQOR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-AQGO | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-AQGR | 20 (40 μL) | 200 μL |
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| BCAT1-PRB3-20-AQAQ | 20 (40 μL) | 200 μL |
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BCAT1 Gene Summary
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
Gene Name: Branched Chain Amino Acid Transaminase 1
Chromosome: CHR12: 24962957 -25102393
Locus: 12p12.1
PRB3 Gene Summary
This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Long" allele. The protein isoforms encoded by this gene are recognized as the "first line of oral defense" against the detrimental effects of polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Nov 2015]
Gene Name: Proline Rich Protein BstNI Subfamily 3
Chromosome: CHR12: 11418856 -11422641
Locus: 12p13.2
Gene Diseases
The BCAT1 PRB3 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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