BCAS3-PRKAA2 Fusion FISH Probe
The BCAS3-PRKAA2 Fusion FISH Probe is used to confirm a fusion of the BCAS3 and PRKAA2 genes. The fusion of the BCAS3 and PRKAA2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCAS3-PRKAA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-RERE | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-REOR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-REGO | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-REGR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-REAQ | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-ORRE | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-OROR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-ORGO | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GORE | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GOOR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GOGO | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GOGR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GRRE | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GROR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GRGO | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GRGR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-AQRE | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-AQOR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-AQGO | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-AQGR | 20 (40 μL) | 200 μL |
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| BCAS3-PRKAA2-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKAA2 Gene Summary
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Gene Name: Protein Kinase AMP-activated Catalytic Subunit Alpha 2
Chromosome: CHR1: 57110989 -57181008
Locus: 1p32.2
BCAS3 Gene Summary
The BCAS3, Microtubule Associated Cell Migration Factor (BCAS3) gene is located on chr17 :58755171-59470199 at 17q23.2.
Gene Name: BCAS3, Microtubule Associated Cell Migration Factor
Chromosome: CHR17: 58755171 -59470199
Locus: 17q23.2
Gene Diseases
The BCAS3 PRKAA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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