BCAS3-GH2 Fusion FISH Probe
The BCAS3-GH2 Fusion FISH Probe is used to confirm a fusion of the BCAS3 and GH2 genes. The fusion of the BCAS3 and GH2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCAS3-GH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-RERE | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-REOR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-REGO | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-REGR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-REAQ | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-ORRE | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-OROR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-ORGO | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GORE | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GOOR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GOGO | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GOGR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GRRE | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GROR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GRGO | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GRGR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-AQRE | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-AQOR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-AQGO | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-AQGR | 20 (40 μL) | 200 μL |
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| BCAS3-GH2-20-AQAQ | 20 (40 μL) | 200 μL |
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GH2 Gene Summary
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq, Jul 2008]
Gene Name: Growth Hormone 2
Chromosome: CHR17: 61957571 -61959223
Locus: 17q23.3
BCAS3 Gene Summary
The BCAS3, Microtubule Associated Cell Migration Factor (BCAS3) gene is located on chr17 :58755171-59470199 at 17q23.2.
Gene Name: BCAS3, Microtubule Associated Cell Migration Factor
Chromosome: CHR17: 58755171 -59470199
Locus: 17q23.2
Gene Diseases
The BCAS3 GH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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