BCAR1-CFDP1 Fusion FISH Probe
The BCAR1-CFDP1 Fusion FISH Probe is used to confirm a fusion of the BCAR1 and CFDP1 genes. The fusion of the BCAR1 and CFDP1 genes has been associated with Liver Hepatocellular Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCAR1-CFDP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-RERE | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-REOR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-REGO | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-REGR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-REAQ | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-ORRE | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-OROR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-ORGO | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GORE | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GOOR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GOGO | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GOGR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GRRE | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GROR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GRGO | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GRGR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-AQRE | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-AQOR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-AQGO | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-AQGR | 20 (40 μL) | 200 μL |
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| BCAR1-CFDP1-20-AQAQ | 20 (40 μL) | 200 μL |
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BCAR1 Gene Summary
The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
Gene Name: BCAR1, Cas Family Scaffolding Protein
Chromosome: CHR16: 75262927 -75301951
Locus: 16q23.1
CFDP1 Gene Summary
The Craniofacial Development Protein 1 (CFDP1) gene is located on chr16 :75327607-75467387 at 16q23.1.
Gene Name: Craniofacial Development Protein 1
Chromosome: CHR16: 75327607 -75467387
Locus: 16q23.1
Gene Diseases
The BCAR1 CFDP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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