BCAP31-HMGB3 Fusion FISH Probe
The BCAP31-HMGB3 Fusion FISH Probe is used to confirm a fusion of the BCAP31 and HMGB3 genes. The fusion of the BCAP31 and HMGB3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCAP31-HMGB3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-RERE | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-REOR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-REGO | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-REGR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-REAQ | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-ORRE | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-OROR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-ORGO | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GORE | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GOOR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GOGO | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GOGR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GRRE | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GROR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GRGO | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GRGR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-AQRE | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-AQOR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-AQGO | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-AQGR | 20 (40 μL) | 200 μL |
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| BCAP31-HMGB3-20-AQAQ | 20 (40 μL) | 200 μL |
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HMGB3 Gene Summary
This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: High Mobility Group Box 3
Chromosome: CHRX: 150151762 -150159248
Locus: Xq28
BCAP31 Gene Summary
This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]
Gene Name: B-cell Receptor Associated Protein 31
Chromosome: CHRX: 152965946 -152990201
Locus: Xq28
Gene Diseases
The BCAP31 HMGB3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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