BBX-KPNA4 Fusion FISH Probe
The BBX-KPNA4 Fusion FISH Probe is used to confirm a fusion of the BBX and KPNA4 genes. The fusion of the BBX and KPNA4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BBX-KPNA4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-RERE | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-REOR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-REGO | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-REGR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-REAQ | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-ORRE | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-OROR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-ORGO | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-ORAQ | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GORE | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GOOR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GOGO | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GOGR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GOAQ | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GRRE | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GROR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GRGO | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GRGR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-GRAQ | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-AQRE | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-AQOR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-AQGO | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-AQGR | 20 (40 μL) | 200 μL |
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| BBX-KPNA4-20-AQAQ | 20 (40 μL) | 200 μL |
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KPNA4 Gene Summary
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]
Gene Name: Karyopherin Subunit Alpha 4
Chromosome: CHR3: 160212782 -160283376
Locus: 3q25.33
BBX Gene Summary
The BBX, HMG-box Containing (BBX) gene is located on chr3 :107241782-107530049 at 3q13.12.
Gene Name: BBX, HMG-box Containing
Chromosome: CHR3: 107241782 -107530049
Locus: 3q13.12
Gene Diseases
The BBX KPNA4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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