BBX-DGKG Fusion FISH Probe
The BBX-DGKG Fusion FISH Probe is used to confirm a fusion of the BBX and DGKG genes. The fusion of the BBX and DGKG genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BBX-DGKG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-RERE | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-REOR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-REGO | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-REGR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-REAQ | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-ORRE | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-OROR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-ORGO | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-ORAQ | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GORE | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GOOR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GOGO | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GOGR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GOAQ | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GRRE | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GROR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GRGO | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GRGR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-GRAQ | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-AQRE | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-AQOR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-AQGO | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-AQGR | 20 (40 μL) | 200 μL |
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| BBX-DGKG-20-AQAQ | 20 (40 μL) | 200 μL |
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DGKG Gene Summary
This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Diacylglycerol Kinase Gamma
Chromosome: CHR3: 185864989 -186080023
Locus: 3q27.2-q27.3
BBX Gene Summary
The BBX, HMG-box Containing (BBX) gene is located on chr3 :107241782-107530049 at 3q13.12.
Gene Name: BBX, HMG-box Containing
Chromosome: CHR3: 107241782 -107530049
Locus: 3q13.12
Gene Diseases
The BBX DGKG Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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