BAZ1A-NKX2-1 Fusion FISH Probe
The BAZ1A-NKX2-1 Fusion FISH Probe is used to confirm a fusion of the BAZ1A and NKX2-1 genes. The fusion of the BAZ1A and NKX2-1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BAZ1A-NKX2-1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-RERE | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-REOR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-REGO | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-REGR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-REAQ | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-ORRE | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-OROR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-ORGO | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GORE | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GOOR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GOGO | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GOGR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GRRE | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GROR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GRGO | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GRGR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-AQRE | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-AQOR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-AQGO | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-AQGR | 20 (40 μL) | 200 μL |
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| BAZ1A-NKX2-1-20-AQAQ | 20 (40 μL) | 200 μL |
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NKX2-1 Gene Summary
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Gene Name: NK2 Homeobox 1
Chromosome: CHR14: 36985603 -36989430
Locus: 14q13.3
BAZ1A Gene Summary
The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010]
Gene Name: Bromodomain Adjacent To Zinc Finger Domain 1A
Chromosome: CHR14: 35221936 -35344853
Locus: 14q13.1-q13.2
Gene Diseases
The BAZ1A NKX2-1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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