BARD1-C6ORF222 Fusion FISH Probe
The BARD1-C6ORF222 Fusion FISH Probe is used to confirm a fusion of the BARD1 and C6ORF222 genes. The fusion of the BARD1 and C6ORF222 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BARD1-C6ORF222-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-RERE | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-REOR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-REGO | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-REGR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-REAQ | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-ORRE | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-OROR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-ORGO | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-ORAQ | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GORE | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GOOR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GOGO | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GOGR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GOAQ | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GRRE | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GROR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GRGO | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GRGR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-GRAQ | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-AQRE | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-AQOR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-AQGO | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-AQGR | 20 (40 μL) | 200 μL |
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| BARD1-C6ORF222-20-AQAQ | 20 (40 μL) | 200 μL |
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BARD1 Gene Summary
This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: BRCA1 Associated RING Domain 1
Chromosome: CHR2: 215593274 -215674428
Locus: 2q35
C6orf222 Gene Summary
The Chromosome 6 Open Reading Frame 222 (C6orf222) gene is located on chr6 :36283534-36304662 at 6p21.31.
Gene Name: Chromosome 6 Open Reading Frame 222
Chromosome: CHR6: 36283534 -36304662
Locus: 6p21.31
Gene Diseases
The BARD1 C6ORF222 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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