BAP1-RILP Fusion FISH Probe
The BAP1-RILP Fusion FISH Probe is used to confirm a fusion of the BAP1 and RILP genes. The fusion of the BAP1 and RILP genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BAP1-RILP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-RERE | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-REOR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-REGO | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-REGR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-REAQ | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-ORRE | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-OROR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-ORGO | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-ORAQ | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GORE | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GOOR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GOGO | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GOGR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GOAQ | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GRRE | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GROR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GRGO | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GRGR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-GRAQ | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-AQRE | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-AQOR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-AQGO | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-AQGR | 20 (40 μL) | 200 μL |
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| BAP1-RILP-20-AQAQ | 20 (40 μL) | 200 μL |
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BAP1 Gene Summary
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
Gene Name: BRCA1 Associated Protein 1
Chromosome: CHR3: 52435024 -52444009
Locus: 3p21.1
RILP Gene Summary
This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011]
Gene Name: Rab Interacting Lysosomal Protein
Chromosome: CHR17: 1549444 -1553392
Locus: 17p13.3
Gene Diseases
The BAP1 RILP Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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