BAIAP2L2-PLA2G6 Fusion FISH Probe
The BAIAP2L2-PLA2G6 Fusion FISH Probe is used to confirm a fusion of the BAIAP2L2 and PLA2G6 genes. The fusion of the BAIAP2L2 and PLA2G6 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BAIAP2L2-PLA2G6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-RERE | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-REOR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-REGO | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-REGR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-REAQ | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-ORRE | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-OROR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-ORGO | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-ORAQ | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GORE | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GOOR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GOGO | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GOGR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GOAQ | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GRRE | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GROR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GRGO | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GRGR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-GRAQ | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-AQRE | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-AQOR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-AQGO | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-AQGR | 20 (40 μL) | 200 μL |
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| BAIAP2L2-PLA2G6-20-AQAQ | 20 (40 μL) | 200 μL |
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PLA2G6 Gene Summary
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
Gene Name: Phospholipase A2 Group VI
Chromosome: CHR22: 38507501 -38577836
Locus: 22q13.1
BAIAP2L2 Gene Summary
The protein encoded by this gene binds phosphoinositides and promotes the formation of planar or curved membrane structures. The encoded protein is found in RAB13-positive vesicles and at intercellular contacts with the plasma membrane. [provided by RefSeq, Dec 2012]
Gene Name: BAI1 Associated Protein 2 Like 2
Chromosome: CHR22: 38480895 -38506676
Locus: 22q13.1
Gene Diseases
The BAIAP2L2 PLA2G6 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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