BAG2-RNF114 Fusion FISH Probe
The BAG2-RNF114 Fusion FISH Probe is used to confirm a fusion of the BAG2 and RNF114 genes. The fusion of the BAG2 and RNF114 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BAG2-RNF114-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-RERE | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-REOR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-REGO | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-REGR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-REAQ | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-ORRE | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-OROR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-ORGO | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-ORAQ | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GORE | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GOOR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GOGO | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GOGR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GOAQ | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GRRE | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GROR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GRGO | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GRGR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-GRAQ | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-AQRE | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-AQOR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-AQGO | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-AQGR | 20 (40 μL) | 200 μL |
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| BAG2-RNF114-20-AQAQ | 20 (40 μL) | 200 μL |
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BAG2 Gene Summary
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
Gene Name: BCL2 Associated Athanogene 2
Chromosome: CHR6: 57037103 -57050012
Locus: 6p12.1
RNF114 Gene Summary
The Ring Finger Protein 114 (RNF114) gene is located on chr20 :48552913-48570422 at 20q13.13.
Gene Name: Ring Finger Protein 114
Chromosome: CHR20: 48552913 -48570422
Locus: 20q13.13
Gene Diseases
The BAG2 RNF114 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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