BACH1-OSBPL8 Fusion FISH Probe
The BACH1-OSBPL8 Fusion FISH Probe is used to confirm a fusion of the BACH1 and OSBPL8 genes. The fusion of the BACH1 and OSBPL8 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BACH1-OSBPL8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-RERE | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-REOR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-REGO | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-REGR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-REAQ | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-ORRE | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-OROR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-ORGO | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-ORAQ | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GORE | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GOOR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GOGO | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GOGR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GOAQ | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GRRE | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GROR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GRGO | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GRGR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-GRAQ | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-AQRE | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-AQOR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-AQGO | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-AQGR | 20 (40 μL) | 200 μL |
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| BACH1-OSBPL8-20-AQAQ | 20 (40 μL) | 200 μL |
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BACH1 Gene Summary
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]
Gene Name: BTB Domain And CNC Homolog 1
Chromosome: CHR21: 30677559 -30734217
Locus: 21q21.3
OSBPL8 Gene Summary
This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Oxysterol Binding Protein Like 8
Chromosome: CHR12: 76745577 -76953589
Locus: 12q21.2
Gene Diseases
The BACH1 OSBPL8 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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