BACE2-WDR81 Fusion FISH Probe
The BACE2-WDR81 Fusion FISH Probe is used to confirm a fusion of the BACE2 and WDR81 genes. The fusion of the BACE2 and WDR81 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BACE2-WDR81-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-RERE | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-REOR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-REGO | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-REGR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-REAQ | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-ORRE | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-OROR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-ORGO | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-ORAQ | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GORE | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GOOR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GOGO | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GOGR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GOAQ | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GRRE | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GROR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GRGO | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GRGR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-GRAQ | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-AQRE | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-AQOR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-AQGO | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-AQGR | 20 (40 μL) | 200 μL |
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| BACE2-WDR81-20-AQAQ | 20 (40 μL) | 200 μL |
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BACE2 Gene Summary
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Beta-site APP-cleaving Enzyme 2
Chromosome: CHR21: 42539727 -42648524
Locus: 21q22.2-q22.3
WDR81 Gene Summary
This gene encodes a multi-domain transmembrane protein which is predominantly expressed in the brain and is thought to play a role in endolysosomal trafficking. Mutations in this gene are associated with an autosomal recessive form of a syndrome exhibiting cerebellar ataxia, cognitive disability, and disequilibrium (CAMRQ2). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Gene Name: WD Repeat Domain 81
Chromosome: CHR17: 1619816 -1641893
Locus: 17p13.3
Gene Diseases
The BACE2 WDR81 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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