B4GALT3-BCAS3 Fusion FISH Probe
The B4GALT3-BCAS3 Fusion FISH Probe is used to confirm a fusion of the B4GALT3 and BCAS3 genes. The fusion of the B4GALT3 and BCAS3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| B4GALT3-BCAS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-RERE | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-REOR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-REGO | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-REGR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-REAQ | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-ORRE | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-OROR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-ORGO | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-ORAQ | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GORE | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GOOR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GOGO | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GOGR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GOAQ | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GRRE | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GROR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GRGO | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GRGR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-GRAQ | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-AQRE | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-AQOR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-AQGO | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-AQGR | 20 (40 μL) | 200 μL |
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| B4GALT3-BCAS3-20-AQAQ | 20 (40 μL) | 200 μL |
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B4GALT3 Gene Summary
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Beta-1,4-galactosyltransferase 3
Chromosome: CHR1: 161141099 -161147758
Locus: 1q23.3
BCAS3 Gene Summary
The BCAS3, Microtubule Associated Cell Migration Factor (BCAS3) gene is located on chr17 :58755171-59470199 at 17q23.2.
Gene Name: BCAS3, Microtubule Associated Cell Migration Factor
Chromosome: CHR17: 58755171 -59470199
Locus: 17q23.2
Gene Diseases
The B4GALT3 BCAS3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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