B3GNT5-ALG3 Fusion FISH Probe
The B3GNT5-ALG3 Fusion FISH Probe is used to confirm a fusion of the B3GNT5 and ALG3 genes. The fusion of the B3GNT5 and ALG3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| B3GNT5-ALG3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-RERE | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-REOR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-REGO | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-REGR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-REAQ | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-ORRE | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-OROR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-ORGO | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-ORAQ | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GORE | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GOOR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GOGO | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GOGR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GOAQ | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GRRE | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GROR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GRGO | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GRGR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-GRAQ | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-AQRE | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-AQOR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-AQGO | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-AQGR | 20 (40 μL) | 200 μL |
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| B3GNT5-ALG3-20-AQAQ | 20 (40 μL) | 200 μL |
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ALG3 Gene Summary
This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Name: ALG3, Alpha-1,3- Mannosyltransferase
Chromosome: CHR3: 183960116 -183967313
Locus: 3q27.1
B3GNT5 Gene Summary
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008]
Gene Name: UDP-GlcNAc:betaGal Beta-1,3-N-acetylglucosaminyltransferase 5
Chromosome: CHR3: 182971031 -182991179
Locus: 3q27.1
Gene Diseases
The B3GNT5 ALG3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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