B3GNT3-INSL3 Fusion FISH Probe
The B3GNT3-INSL3 Fusion FISH Probe is used to confirm a fusion of the B3GNT3 and INSL3 genes. The fusion of the B3GNT3 and INSL3 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| B3GNT3-INSL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-RERE | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-REOR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-REGO | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-REGR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-REAQ | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-ORRE | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-OROR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-ORGO | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-ORAQ | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GORE | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GOOR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GOGO | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GOGR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GOAQ | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GRRE | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GROR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GRGO | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GRGR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-GRAQ | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-AQRE | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-AQOR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-AQGO | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-AQGR | 20 (40 μL) | 200 μL |
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| B3GNT3-INSL3-20-AQAQ | 20 (40 μL) | 200 μL |
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INSL3 Gene Summary
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Name: Insulin Like 3
Chromosome: CHR19: 17927321 -17932320
Locus: 19p13.11
B3GNT3 Gene Summary
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008]
Gene Name: UDP-GlcNAc:betaGal Beta-1,3-N-acetylglucosaminyltransferase 3
Chromosome: CHR19: 17905918 -17924385
Locus: 19p13.11
Gene Diseases
The B3GNT3 INSL3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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