B2M-CCT5 Fusion FISH Probe
The B2M-CCT5 Fusion FISH Probe is used to confirm a fusion of the B2M and CCT5 genes. The fusion of the B2M and CCT5 genes has been associated with Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| B2M-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| B2M-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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B2M Gene Summary
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
Gene Name: Beta-2-microglobulin
Chromosome: CHR15: 45003684 -45010357
Locus: 15q21.1
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The B2M CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lymphoid Neoplasm Diffuse Large B-cell Lymphoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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