AXIN1-BBX Fusion FISH Probe
The AXIN1-BBX Fusion FISH Probe is used to confirm a fusion of the AXIN1 and BBX genes. The fusion of the AXIN1 and BBX genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AXIN1-BBX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-RERE | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-REOR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-REGO | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-REGR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-REAQ | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-ORRE | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-OROR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-ORGO | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-ORAQ | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GORE | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GOOR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GOGO | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GOGR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GOAQ | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GRRE | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GROR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GRGO | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GRGR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-GRAQ | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-AQRE | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-AQOR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-AQGO | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-AQGR | 20 (40 μL) | 200 μL |
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| AXIN1-BBX-20-AQAQ | 20 (40 μL) | 200 μL |
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AXIN1 Gene Summary
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: Axin 1
Chromosome: CHR16: 337439 -402676
Locus: 16p13.3
BBX Gene Summary
The BBX, HMG-box Containing (BBX) gene is located on chr3 :107241782-107530049 at 3q13.12.
Gene Name: BBX, HMG-box Containing
Chromosome: CHR3: 107241782 -107530049
Locus: 3q13.12
Gene Diseases
The AXIN1 BBX Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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