AUTS2-SEMA3A Fusion FISH Probe
The AUTS2-SEMA3A Fusion FISH Probe is used to confirm a fusion of the AUTS2 and SEMA3A genes. The fusion of the AUTS2 and SEMA3A genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AUTS2-SEMA3A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-RERE | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-REOR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-REGO | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-REGR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-REAQ | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-ORRE | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-OROR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-ORGO | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-ORAQ | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GORE | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GOOR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GOGO | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GOGR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GOAQ | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GRRE | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GROR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GRGO | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GRGR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-GRAQ | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-AQRE | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-AQOR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-AQGO | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-AQGR | 20 (40 μL) | 200 μL |
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| AUTS2-SEMA3A-20-AQAQ | 20 (40 μL) | 200 μL |
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SEMA3A Gene Summary
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
Gene Name: Semaphorin 3A
Chromosome: CHR7: 83587658 -83824217
Locus: 7q21.11
AUTS2 Gene Summary
This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2014]
Gene Name: AUTS2, Activator Of Transcription And Developmental Regulator
Chromosome: CHR7: 69063905 -70257885
Locus: 7q11.22
Gene Diseases
The AUTS2 SEMA3A Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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