AURKB-MYH10 Fusion FISH Probe
The AURKB-MYH10 Fusion FISH Probe is used to confirm a fusion of the AURKB and MYH10 genes. The fusion of the AURKB and MYH10 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AURKB-MYH10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-RERE | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-REOR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-REGO | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-REGR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-REAQ | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-ORRE | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-OROR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-ORGO | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-ORAQ | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GORE | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GOOR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GOGO | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GOGR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GOAQ | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GRRE | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GROR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GRGO | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GRGR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-GRAQ | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-AQRE | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-AQOR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-AQGO | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-AQGR | 20 (40 μL) | 200 μL |
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| AURKB-MYH10-20-AQAQ | 20 (40 μL) | 200 μL |
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MYH10 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 10
Chromosome: CHR17: 8377529 -8534036
Locus: 17p13.1
AURKB Gene Summary
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Name: Aurora Kinase B
Chromosome: CHR17: 8108048 -8113883
Locus: 17p13.1
Gene Diseases
The AURKB MYH10 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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