ATXN10-FBLN1 Fusion FISH Probe
The ATXN10-FBLN1 Fusion FISH Probe is used to confirm a fusion of the ATXN10 and FBLN1 genes. The fusion of the ATXN10 and FBLN1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATXN10-FBLN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-RERE | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-REOR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-REGO | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-REGR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-REAQ | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-ORRE | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-OROR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-ORGO | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GORE | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GOOR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GOGO | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GOGR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GRRE | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GROR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GRGO | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GRGR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-AQRE | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-AQOR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-AQGO | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-AQGR | 20 (40 μL) | 200 μL |
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| ATXN10-FBLN1-20-AQAQ | 20 (40 μL) | 200 μL |
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FBLN1 Gene Summary
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
Gene Name: Fibulin 1
Chromosome: CHR22: 45898718 -45997014
Locus: 22q13.31
ATXN10 Gene Summary
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]
Gene Name: Ataxin 10
Chromosome: CHR22: 46067677 -46241187
Locus: 22q13.31
Gene Diseases
The ATXN10 FBLN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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