ATP6V0A1-MB Fusion FISH Probe
The ATP6V0A1-MB Fusion FISH Probe is used to confirm a fusion of the ATP6V0A1 and MB genes. The fusion of the ATP6V0A1 and MB genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP6V0A1-MB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-RERE | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-REOR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-REGO | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-REGR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-OROR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GORE | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GROR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP6V0A1-MB-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP6V0A1 Gene Summary
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: ATPase H+ Transporting V0 Subunit A1
Chromosome: CHR17: 40610861 -40674597
Locus: 17q21.2
MB Gene Summary
This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Myoglobin
Chromosome: CHR22: 36002810 -36019401
Locus: 22q12.3
Gene Diseases
The ATP6V0A1 MB Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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