ATP6AP1-OPN1LW Fusion FISH Probe
The ATP6AP1-OPN1LW Fusion FISH Probe is used to confirm a fusion of the ATP6AP1 and OPN1LW genes. The fusion of the ATP6AP1 and OPN1LW genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATP6AP1-OPN1LW-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ATP6AP1-OPN1LW-20-AQAQ | 20 (40 μL) | 200 μL |
|
ATP6AP1 Gene Summary
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
Gene Name: ATPase H+ Transporting Accessory Protein 1
Chromosome: CHRX: 153656977 -153664862
Locus: Xq28
OPN1LW Gene Summary
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008]
Gene Name: Opsin 1, Long Wave Sensitive
Chromosome: CHRX: 153409724 -153424507
Locus: Xq28
Gene Diseases
The ATP6AP1 OPN1LW Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|