ATP6AP1-CCT5 Fusion FISH Probe
The ATP6AP1-CCT5 Fusion FISH Probe is used to confirm a fusion of the ATP6AP1 and CCT5 genes. The fusion of the ATP6AP1 and CCT5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP6AP1-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP6AP1-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP6AP1 Gene Summary
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
Gene Name: ATPase H+ Transporting Accessory Protein 1
Chromosome: CHRX: 153656977 -153664862
Locus: Xq28
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The ATP6AP1 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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