ATP5L-AHCYL2 Fusion FISH Probe
The ATP5L-AHCYL2 Fusion FISH Probe is used to confirm a fusion of the ATP5L and AHCYL2 genes. The fusion of the ATP5L and AHCYL2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP5L-AHCYL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-RERE | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-REOR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-REGO | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-REGR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-OROR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GORE | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GROR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP5L-AHCYL2-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5L Gene Summary
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the g subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit G
Chromosome: CHR11: 118272103 -118280562
Locus: 11q23.3
AHCYL2 Gene Summary
The protein encoded by this gene acts as a homotetramer and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Adenosylhomocysteinase Like 2
Chromosome: CHR7: 128864854 -129070052
Locus: 7q32.1
Gene Diseases
The ATP5L AHCYL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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