ATP2B1-IKBIP Fusion FISH Probe
The ATP2B1-IKBIP Fusion FISH Probe is used to confirm a fusion of the ATP2B1 and IKBIP genes. The fusion of the ATP2B1 and IKBIP genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP2B1-IKBIP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-RERE | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-REOR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-REGO | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-REGR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-OROR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GORE | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GROR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP2B1-IKBIP-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP2B1 Gene Summary
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ATPase Plasma Membrane Ca2+ Transporting 1
Chromosome: CHR12: 89981825 -90049844
Locus: 12q21.33
IKBIP Gene Summary
The IKBKB Interacting Protein (IKBIP) gene is located on chr12 :99007181-99038589 at 12q23.1.
Gene Name: IKBKB Interacting Protein
Chromosome: CHR12: 99007181 -99038589
Locus: 12q23.1
Gene Diseases
The ATP2B1 IKBIP Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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