ATP2A2-EP400 Fusion FISH Probe
The ATP2A2-EP400 Fusion FISH Probe is used to confirm a fusion of the ATP2A2 and EP400 genes. The fusion of the ATP2A2 and EP400 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP2A2-EP400-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-RERE | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-REOR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-REGO | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-REGR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-OROR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GORE | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GROR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP2A2-EP400-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP2A2 Gene Summary
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]
Gene Name: ATPase Sarcoplasmic/endoplasmic Reticulum Ca2+ Transporting 2
Chromosome: CHR12: 110719031 -110788897
Locus: 12q24.11
EP400 Gene Summary
The E1A Binding Protein P400 (EP400) gene is located on chr12 :132434464-132565011 at 12q24.33.
Gene Name: E1A Binding Protein P400
Chromosome: CHR12: 132434464 -132565011
Locus: 12q24.33
Gene Diseases
The ATP2A2 EP400 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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