ATP1B1-RCSD1 Fusion FISH Probe
The ATP1B1-RCSD1 Fusion FISH Probe is used to confirm a fusion of the ATP1B1 and RCSD1 genes. The fusion of the ATP1B1 and RCSD1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP1B1-RCSD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-RERE | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-REOR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-REGO | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-REGR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-OROR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GORE | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GROR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP1B1-RCSD1-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP1B1 Gene Summary
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
Gene Name: ATPase Na+/K+ Transporting Subunit Beta 1
Chromosome: CHR1: 169075946 -169101960
Locus: 1q24.2
RCSD1 Gene Summary
The RCSD Domain Containing 1 (RCSD1) gene is located on chr1 :167599473-167675486 at 1q24.2.
Gene Name: RCSD Domain Containing 1
Chromosome: CHR1: 167599473 -167675486
Locus: 1q24.2
Gene Diseases
The ATP1B1 RCSD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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