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ATP1A1-VANGL1 Fusion FISH Probe

The ATP1A1-VANGL1 Fusion FISH Probe is used to confirm a fusion of the ATP1A1 and VANGL1 genes. The fusion of the ATP1A1 and VANGL1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ATP1A1-VANGL1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-RERE 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-REOR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-REGO 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-REGR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-REAQ 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-ORRE 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-OROR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-ORGO 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-ORAQ 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GORE 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GOOR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GOGO 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GOGR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GOAQ 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GRRE 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GROR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GRGO 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GRGR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-GRAQ 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-AQRE 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-AQOR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-AQGO 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-AQGR 20 (40 μL) 200 μL
ATP1A1-VANGL1-20-AQAQ 20 (40 μL) 200 μL

ATP1A1 Gene Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Gene Name: ATPase Na+/K+ Transporting Subunit Alpha 1

Chromosome: CHR1: 116915794 -116947396

Locus: 1p13.1

VANGL1 Gene Summary

This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Gene Name: VANGL Planar Cell Polarity Protein 1

Chromosome: CHR1: 116184573 -116240845

Locus: 1p13.1

Gene Diseases

The ATP1A1 VANGL1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.