ATP1A1-FN1 Fusion FISH Probe
The ATP1A1-FN1 Fusion FISH Probe is used to confirm a fusion of the ATP1A1 and FN1 genes. The fusion of the ATP1A1 and FN1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP1A1-FN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-RERE | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-REOR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-REGO | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-REGR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-OROR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GORE | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GROR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP1A1-FN1-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP1A1 Gene Summary
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: ATPase Na+/K+ Transporting Subunit Alpha 1
Chromosome: CHR1: 116915794 -116947396
Locus: 1p13.1
FN1 Gene Summary
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]
Gene Name: Fibronectin 1
Chromosome: CHR2: 216225178 -216300791
Locus: 2q35
Gene Diseases
The ATP1A1 FN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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