ATP1A1-DDX21 Fusion FISH Probe
The ATP1A1-DDX21 Fusion FISH Probe is used to confirm a fusion of the ATP1A1 and DDX21 genes. The fusion of the ATP1A1 and DDX21 genes has been associated with Stomach Adenocarcinoma, and Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP1A1-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP1A1-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP1A1 Gene Summary
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: ATPase Na+/K+ Transporting Subunit Alpha 1
Chromosome: CHR1: 116915794 -116947396
Locus: 1p13.1
DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
Gene Diseases
The ATP1A1 DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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