ATP11B-NET1 Fusion FISH Probe
The ATP11B-NET1 Fusion FISH Probe is used to confirm a fusion of the ATP11B and NET1 genes. The fusion of the ATP11B and NET1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP11B-NET1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-RERE | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-REOR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-REGO | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-REGR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-OROR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GORE | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GROR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP11B-NET1-20-AQAQ | 20 (40 μL) | 200 μL |
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NET1 Gene Summary
This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Gene Name: Neuroepithelial Cell Transforming 1
Chromosome: CHR10: 5454517 -5500426
Locus: 10p15.1
ATP11B Gene Summary
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Gene Name: ATPase Phospholipid Transporting 11B (putative)
Chromosome: CHR3: 182511290 -182639421
Locus: 3q26.33
Gene Diseases
The ATP11B NET1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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