ATP11B-MED10 Fusion FISH Probe
The ATP11B-MED10 Fusion FISH Probe is used to confirm a fusion of the ATP11B and MED10 genes. The fusion of the ATP11B and MED10 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP11B-MED10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-RERE | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-REOR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-REGO | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-REGR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-OROR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GORE | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GROR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP11B-MED10-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP11B Gene Summary
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Gene Name: ATPase Phospholipid Transporting 11B (putative)
Chromosome: CHR3: 182511290 -182639421
Locus: 3q26.33
MED10 Gene Summary
MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Gene Name: Mediator Complex Subunit 10
Chromosome: CHR5: 6372038 -6378639
Locus: 5p15.31
Gene Diseases
The ATP11B MED10 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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