ATP11B-FXR1 Fusion FISH Probe
The ATP11B-FXR1 Fusion FISH Probe is used to confirm a fusion of the ATP11B and FXR1 genes. The fusion of the ATP11B and FXR1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP11B-FXR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-RERE | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-REOR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-REGO | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-REGR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-OROR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GORE | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GROR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP11B-FXR1-20-AQAQ | 20 (40 μL) | 200 μL |
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FXR1 Gene Summary
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: FMR1 Autosomal Homolog 1
Chromosome: CHR3: 180630233 -180700539
Locus: 3q26.33
ATP11B Gene Summary
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Gene Name: ATPase Phospholipid Transporting 11B (putative)
Chromosome: CHR3: 182511290 -182639421
Locus: 3q26.33
Gene Diseases
The ATP11B FXR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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