ATG7-ARMC3 Fusion FISH Probe
The ATG7-ARMC3 Fusion FISH Probe is used to confirm a fusion of the ATG7 and ARMC3 genes. The fusion of the ATG7 and ARMC3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATG7-ARMC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-RERE | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-REOR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-REGO | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-REGR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-REAQ | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-ORRE | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-OROR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-ORGO | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GORE | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GOOR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GOGO | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GOGR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GRRE | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GROR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GRGO | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GRGR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-AQRE | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-AQOR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-AQGO | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-AQGR | 20 (40 μL) | 200 μL |
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| ATG7-ARMC3-20-AQAQ | 20 (40 μL) | 200 μL |
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ATG7 Gene Summary
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Name: Autophagy Related 7
Chromosome: CHR3: 11314009 -11599139
Locus: 3p25.3
ARMC3 Gene Summary
Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).[supplied by OMIM, Mar 2008]
Gene Name: Armadillo Repeat Containing 3
Chromosome: CHR10: 23216953 -23326514
Locus: 10p12.2
Gene Diseases
The ATG7 ARMC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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