ATG16L1-NGEF Fusion FISH Probe
The ATG16L1-NGEF Fusion FISH Probe is used to confirm a fusion of the ATG16L1 and NGEF genes. The fusion of the ATG16L1 and NGEF genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATG16L1-NGEF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-RERE | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-REOR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-REGO | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-REGR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-REAQ | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-ORRE | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-OROR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-ORGO | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GORE | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GOOR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GOGO | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GOGR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GRRE | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GROR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GRGO | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GRGR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-AQRE | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-AQOR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-AQGO | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-AQGR | 20 (40 μL) | 200 μL |
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| ATG16L1-NGEF-20-AQAQ | 20 (40 μL) | 200 μL |
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NGEF Gene Summary
The Neuronal Guanine Nucleotide Exchange Factor (NGEF) gene is located on chr2 :233743395-233877951 at 2q37.1.
Gene Name: Neuronal Guanine Nucleotide Exchange Factor
Chromosome: CHR2: 233743395 -233877951
Locus: 2q37.1
ATG16L1 Gene Summary
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Gene Name: Autophagy Related 16 Like 1
Chromosome: CHR2: 234160216 -234204320
Locus: 2q37.1
Gene Diseases
The ATG16L1 NGEF Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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