ATF7-ATP5G2 Fusion FISH Probe
The ATF7-ATP5G2 Fusion FISH Probe is used to confirm a fusion of the ATF7 and ATP5G2 genes. The fusion of the ATF7 and ATP5G2 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATF7-ATP5G2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-RERE | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-REOR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-REGO | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-REGR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-REAQ | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-ORRE | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-OROR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-ORGO | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GORE | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GOOR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GOGO | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GOGR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GRRE | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GROR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GRGO | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GRGR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-AQRE | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-AQOR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-AQGO | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-AQGR | 20 (40 μL) | 200 μL |
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| ATF7-ATP5G2-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5G2 Gene Summary
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. This gene has multiple pseudogenes. [provided by RefSeq, Jan 2018]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit C2 (subunit 9)
Chromosome: CHR12: 54058943 -54070512
Locus: 12q13.13
ATF7 Gene Summary
The Activating Transcription Factor 7 (ATF7) gene is located on chr12 :53905842-54020199 at 12q13.13.
Gene Name: Activating Transcription Factor 7
Chromosome: CHR12: 53905842 -54020199
Locus: 12q13.13
Gene Diseases
The ATF7 ATP5G2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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