ATF3-CDH20 Fusion FISH Probe
The ATF3-CDH20 Fusion FISH Probe is used to confirm a fusion of the ATF3 and CDH20 genes. The fusion of the ATF3 and CDH20 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATF3-CDH20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-RERE | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-REOR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-REGO | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-REGR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-REAQ | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-ORRE | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-OROR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-ORGO | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GORE | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GOOR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GOGO | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GOGR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GRRE | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GROR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GRGO | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GRGR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-AQRE | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-AQOR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-AQGO | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-AQGR | 20 (40 μL) | 200 μL |
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| ATF3-CDH20-20-AQAQ | 20 (40 μL) | 200 μL |
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ATF3 Gene Summary
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]
Gene Name: Activating Transcription Factor 3
Chromosome: CHR1: 212738675 -212794119
Locus: 1q32.3
CDH20 Gene Summary
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
Gene Name: Cadherin 20
Chromosome: CHR18: 59157774 -59222365
Locus: 18q21.33
Gene Diseases
The ATF3 CDH20 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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