ATE1-DNAJB12 Fusion FISH Probe
The ATE1-DNAJB12 Fusion FISH Probe is used to confirm a fusion of the ATE1 and DNAJB12 genes. The fusion of the ATE1 and DNAJB12 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATE1-DNAJB12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-RERE | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-REOR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-REGO | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-REGR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-REAQ | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-ORRE | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-OROR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-ORGO | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GORE | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GOOR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GOGO | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GOGR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GRRE | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GROR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GRGO | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GRGR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-AQRE | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-AQOR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-AQGO | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-AQGR | 20 (40 μL) | 200 μL |
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| ATE1-DNAJB12-20-AQAQ | 20 (40 μL) | 200 μL |
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ATE1 Gene Summary
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Name: Arginyltransferase 1
Chromosome: CHR10: 123502624 -123687546
Locus: 10q26.13
DNAJB12 Gene Summary
DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member B12
Chromosome: CHR10: 74092587 -74114907
Locus: 10q22.1
Gene Diseases
The ATE1 DNAJB12 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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