ATAD2B-ITSN2 Fusion FISH Probe
The ATAD2B-ITSN2 Fusion FISH Probe is used to confirm a fusion of the ATAD2B and ITSN2 genes. The fusion of the ATAD2B and ITSN2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATAD2B-ITSN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-RERE | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-REOR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-REGO | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-REGR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-REAQ | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-ORRE | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-OROR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-ORGO | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GORE | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GOOR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GOGO | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GOGR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GRRE | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GROR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GRGO | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GRGR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-AQRE | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-AQOR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-AQGO | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-AQGR | 20 (40 μL) | 200 μL |
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| ATAD2B-ITSN2-20-AQAQ | 20 (40 μL) | 200 μL |
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ITSN2 Gene Summary
This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017]
Gene Name: Intersectin 2
Chromosome: CHR2: 24425734 -24583397
Locus: 2p23.3
ATAD2B Gene Summary
The protein encoded by this gene belongs to the AAA ATPase family. This family member includes an N-terminal bromodomain. It has been found to be localized to the nucleus, partly to replication sites, consistent with a chromatin-related function. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ATPase Family, AAA Domain Containing 2B
Chromosome: CHR2: 23971533 -24149936
Locus: 2p24.1-p23.3
Gene Diseases
The ATAD2B ITSN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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