ASXL2-HSPH1 Fusion FISH Probe
The ASXL2-HSPH1 Fusion FISH Probe is used to confirm a fusion of the ASXL2 and HSPH1 genes. The fusion of the ASXL2 and HSPH1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ASXL2-HSPH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-RERE | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-REOR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-REGO | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-REGR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-REAQ | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-ORRE | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-OROR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-ORGO | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GORE | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GOOR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GOGO | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GOGR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GRRE | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GROR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GRGO | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GRGR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-AQRE | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-AQOR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-AQGO | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-AQGR | 20 (40 μL) | 200 μL |
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| ASXL2-HSPH1-20-AQAQ | 20 (40 μL) | 200 μL |
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HSPH1 Gene Summary
This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]
Gene Name: Heat Shock Protein Family H (Hsp110) Member 1
Chromosome: CHR13: 31710762 -31736117
Locus: 13q12.3
ASXL2 Gene Summary
This gene encodes a member of a family of epigenetic regulators that bind various histone-modifying enzymes and are involved in the assembly of transcription factors at specific genomic loci. Naturally occurring mutations in this gene are associated with cancer in several tissue types (breast, bladder, pancreas, ovary, prostate, and blood). This gene plays an important role in neurodevelopment, cardiac function, adipogenesis, and osteoclastogenesis. [provided by RefSeq, Feb 2017]
Gene Name: Additional Sex Combs Like 2, Transcriptional Regulator
Chromosome: CHR2: 25962252 -26101312
Locus: 2p23.3
Gene Diseases
The ASXL2 HSPH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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