ASCC3-WASF1 Fusion FISH Probe
The ASCC3-WASF1 Fusion FISH Probe is used to confirm a fusion of the ASCC3 and WASF1 genes. The fusion of the ASCC3 and WASF1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ASCC3-WASF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-RERE | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-REOR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-REGO | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-REGR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-REAQ | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-ORRE | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-OROR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-ORGO | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GORE | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GOOR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GOGO | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GOGR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GRRE | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GROR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GRGO | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GRGR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-AQRE | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-AQOR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-AQGO | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-AQGR | 20 (40 μL) | 200 μL |
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| ASCC3-WASF1-20-AQAQ | 20 (40 μL) | 200 μL |
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WASF1 Gene Summary
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: WAS Protein Family Member 1
Chromosome: CHR6: 110421021 -110501207
Locus: 6q21
ASCC3 Gene Summary
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Activating Signal Cointegrator 1 Complex Subunit 3
Chromosome: CHR6: 100956607 -101329224
Locus: 6q16.3
Gene Diseases
The ASCC3 WASF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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