ASCC3-TPD52L1 Fusion FISH Probe
The ASCC3-TPD52L1 Fusion FISH Probe is used to confirm a fusion of the ASCC3 and TPD52L1 genes. The fusion of the ASCC3 and TPD52L1 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ASCC3-TPD52L1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-RERE | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-REOR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-REGO | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-REGR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-REAQ | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-ORRE | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-OROR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-ORGO | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GORE | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GOOR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GOGO | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GOGR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GRRE | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GROR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GRGO | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GRGR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-AQRE | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-AQOR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-AQGO | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-AQGR | 20 (40 μL) | 200 μL |
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| ASCC3-TPD52L1-20-AQAQ | 20 (40 μL) | 200 μL |
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TPD52L1 Gene Summary
This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016]
Gene Name: Tumor Protein D52 Like 1
Chromosome: CHR6: 125474878 -125584644
Locus: 6q22.31
ASCC3 Gene Summary
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Activating Signal Cointegrator 1 Complex Subunit 3
Chromosome: CHR6: 100956607 -101329224
Locus: 6q16.3
Gene Diseases
The ASCC3 TPD52L1 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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